Why resurrecting near-replicas of extinct woolly mammoths might work

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Wowolly mammothsthe iconic giants of the last ice age, died out around 4,000 years ago.

But a company is trying to revive the species – or at least something like it – and the scientist leading the project envisions thousands of these animals roaming the Arctic.

Colossal Biosciences is a start-up launched by tech entrepreneur Ben Lamm and renowned geneticist George Church that aims to resurrect the woolly mammoth, or more specifically, create a genetically modified mammoth. asian elephant which will be cold hardy and have all the basic biological traits of its extinct parent.

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[Church] said Colossal plans to do a number of [gene] changes in cells taken from Asian elephants, an endangered species that is the woolly mammoth’s closest living relative, sharing about 99.6% of its DNA.

“Indeed, the Asian elephant and the woolly mammoth are closer to each other than either of them is to the East African,” Church said. Newsweek.

To determine what changes to make, Colossal researchers need to compare the genomes of elephants to those of the woolly mammoth to identify key differences. Fortunately, some mammoth remains have been remarkably well preserved, with some tissue samples containing intact DNA from which researchers can construct at least partial genomes.

This is an excerpt. Read the original article here

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